The Facts:
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Vitamin E reduced the frequency and severity of hot flashes in a well-controlled trial of 51 menopausal women.
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At a dosage of 400IU daily for 4 weeks, vitamin E reduced the daily frequency of hot flashes from 5 to 3 and their severity score from 2.37 to 1.80 compared with placebo.
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Based on the results of this study the authors recommended vitamin E for the treatment of hot flashes in menopause.
Dr Shaun Holt: Hot flashes are one of the defining features of the menopause, and although this may sound trivial if you have not experienced them, they can be extremely unpleasant. As we have discussed elsewhere in this issue, HRT is not without risks and this good little study showed that vitamin E was safe and effective. The study design was very good, in that the 51 participants received both treatments, separated by what is called a washout period, when the first treatment is stopped and washes out of the body before the second treatment is given.
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