Uptake and early outcomes of a meal replacement intervention in an ethnically diverse adult population living with obesity and significant comorbidity
Authors: Shand J et al.
Summary: A meal replacement intervention delivered in a specialist service achieved clinically meaningful weight loss and improved metabolic and psychological outcomes in a predominantly Māori and Pacific population of adults with obesity and significant comorbidities. Participants (n = 128) had been declined bariatric surgery, were young adults with type 2 diabetes, or had been deferred from a corneal transplant because of their weight. Participants received a 12-week, meal replacement low energy diet, with adjunctive obesity medications available under pre-specified criteria. At baseline, mean body weight was 145.0 kg, body mass index was 49.9 kg/m2, and 73% of participants were receiving treatment for type 2 diabetes (mean glycosylated haemoglobin [HbA1c] 67.6 mmol/mol). Overall, 72% of participants completed the intervention, and achieved a mean weight loss of 10.9 kg. Among those with diabetes, 67% completed the intervention, with 33% achieving an HbA1c <50 mmol/mol on no diabetes medication. Mean psychological and quality of life scores improved.
Reference: Diabetes Obes Metab. 2026;28(5):3924-3932.
Abstract
Foetal movement information and maternal concerns in the third trimester
Authors: Bradford BF et al.
Summary: Foetal movement worries are common for women in the third trimester of pregnancy in New Zealand, but Māori and Pacific women are less likely to seek advice when concerned than European women, according to a survey of 1640 women with singleton pregnancies. Of the surveyed population, 63.5% were European, 16.2% were Māori and 7.3% were Pacific peoples. Median gestation time was 31 weeks, 55.9% were nulliparous, and 83.3% had been concerned about foetal movement. Adjusted odds ratios for seeking advice when concerned were 0.69 (95% CI 0.51%-0.93%; p = 0.02) for Māori and 0.58 (95% CI 0.38%-0.88%; p = 0.01) for Pacific compared with European women. Advice seeking was also less likely when a doctor was the main maternity provider compared with a midwife (adjusted odds ratio 0.59; 95% CI 0.39%-0.92%, p = 0.02), and in those who received fewer compared with the recommended number of antenatal visits (adjusted odd ratio 0.55; 95% CI 0.34%-0.88%; p = 0.01).
Reference: Aust N Z J Obstet Gynaecol. 2026;66(2):e70122.
Abstract